SIngapore Medical FOundation AI model (SIMFONI)
SIMFONI is Singapore’s national programme building healthcare AI models grounded in local clinical guidelines and Asian patient data.
Use Case 1: Clinical Decision Support for Primary Care
Developing AI-enabled clinical decision support tools to support personalised, evidence-based care across primary and selected specialist settings in Singapore.

Use Case 2: Multimodal FM for Ophthalmology
SIMFONI is developing multimodal foundation models that combine medical images and clinical data, with ophthalmology as the initial focus for deployment.

Use Case 3: Patient Coaching & Assistive AI
SIMFONI is developing AI-driven patient coaching tools that use foundation models and large language models to support healthy behaviours and treatment adherence.

Core Foundations
SIMFONI's Core Foundations are the shared groundwork that every SIMFONI use case depends on.

Data Standardisation and Curation
Bringing together Singapore’s three public healthcare clusters, SIMFONI defines a standardised minimum dataset for healthcare foundation model development. This enables scalable AI development, supports ethical use, interoperability, and clinical deployment.

Evaluation, Ethics & Responsible AI
Establishing robust evaluation, ethical, and governance frameworks, SIMFONI ensures the safe and responsible use of models in healthcare while supporting privacy, patient safety, and AI deployment aligned with Singapore’s context.
